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. 2017 Dec 21;6(12):e007320. doi: 10.1161/JAHA.117.007320

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© 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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AF susceptibility and electrophysiological parameters changes. A and B, Examples of AF induction attempts in (A) a control rat and (B) a CIA rat. C, AF inducibility. D, AF duration. E, AERP. F, Intra‐atrium CT. G and H, AF duration was significantly and positively correlated with the serum levels of IL‐6 (interleukin 6; r=0.82, P<0.01) and TNF‐α (tumor necrosis factor α; r=0.84, P<0.01). *P<0.05, **P<0.01, ***P<0.001, vs the CON group, n=10 per group. AERP indicates atrial effective refractory period; AF, atrial fibrillation; CIA, collagen‐induced arthritis; CON, control; CT, conduction time; EGM, electrogram; SR, sinus rhythm.