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. 2017 Dec 21;6(12):e007320. doi: 10.1161/JAHA.117.007320

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© 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Atrial sympathetic remodeling induced by collagen‐induced arthritis (CIA). A through D, Atrial immunostaining and mean density of GAP43 (growth associated protein 43)–positive nerves (A and B) and TH (tyrosine hydroxylase)–positive nerves (C and D), n=8 per group. E through G, Representative Western blots and quantification of protein expressions of GAP43, TH, and NGF (nerve growth factor) in atrial tissues; n=6 per group. ***P<0.001, vs the control (CON) group. Scale bar=50 μm. Arrows indicate the GAP43‐ and TH‐positive nerves.