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. 2017 Nov 29;2(1):63–76. doi: 10.1210/js.2017-00400

Figure 4.

Figure 4.

Serum TSH in male BALB/c and NOD.H2h4 mice exposed to iodized water for 16 weeks. TSH was measured by radioimmunoassay [24] and is expressed as mU/L; the number of sera tested is given in parentheses. The hatched lines provide a “yardstick” for TSH values in untreated recombinant inbred male mice strains (CXB, BXH, and AXB/BXA); mean + 2 SD (n = 51, pooled data from [25]). TSH levels in male BALB/c and NOD.H2h4 mice on iodide supplementation are not significantly (ns) different, but are higher than in recombinant inbred males (analysis of variance, P < 0.05). “Pool” comprises small aliquots of sera from five male BALB/c mice to provide sufficient volume (50 uL) for assay. Note this value is shown for interest and is not used for statistical analysis. T4 values for male NOD.H2h4 mice after 16 weeks on NaI were included in a previous study [20].