Table 6.

Changes in excitatory and inhibitory synaptic transmission after mDEO expressed as % change from control neurons of the hemisphere contralateral to the open eye.

Layer	sEPSC charge		sEPSC frequency		sEPSC amplitude		sIPSC charge		sIPSC frequency		sIPSC amplitude		E/I ratio
	mDEO P17	mDEO P21	mDEO P17	mDEO P21	mDEO P17	mDEO P21	mDEO P17	mDEO P21	mDEO P17	mDEO P21	mDEO P17	mDEO P21	mDEO P17	mDEO P21
L2/3	50 ± 6; *p < 0.001	73 ± 6; *p = 0.03	58 ± 9; p = 0.003	99 ± 6; p = 0.9	99 ± 10; p = 0.9	76 ± 5; *p = 0.01	131 ± 23; p = 0.2	75 ± 7; *p = 0.02	123 ± 16; p = 0.2	98 ± 4; p = 0.9	108 ± 12; p = 0.6	83 ± 5;*p = 0.04	40 ± 7; *p < 0.001	104 ± 13; p = 0.7
L4	120 ± 9; p = 0.2	164 ± 18; *p = 0.01	97 ± 8; p = 0.8	97 ± 9; p = 0.9	111 ± 7; p = 0.2	130 ± 9; *p = 0.01	147 ± 16; *p = 0.01	147 ± 16; *p = 0.01	101 ± 8; p = 0.9	142 ± 16; *p = 0.04	134 ± 8; *p = 0.003	109 ± 7; p = 0.3	72 ± 9; *p = 0.04	116 ± 14; p = 0.4
L5	132 ± 16; p = 0.15	85 ± 16; p = 0.5	131 ± 21; p = 0.3	72 ± 15; p = 0.5	88 ± 5; p = 0.1	93 ± 7; p = 0.5	80 ± 8; p = 0.2	70 ± 9; p = 0.09	80 ± 8; p = 0.3	87 ± 7; p = 0.2	103 ± 8; p = 0.7	76 ± 4; *p = 0.04	160 ± 29; p = 0.1	112 ± 15; p = 0.6
L6	78 ± 16; p = 0.4	177 ± 33; *p = 0.02	71 ± 13; p = 0.2	170 ± 19 *p = 0.003	99 ± 7; p = 0.9	90 ± 5; p = 0.2	86 ± 18; p = 0.16	97 ± 19; p = 0.9	80 ± 14; p = 0.5	107 ± 14; p = 0.7	106 ± 10; p = 0.6	100 ± 8; p = 0.9	81 ± 21; p = 0.5	171 ± 36; p = 0.06

Results are expressed as mean % change ± SEM. *Statistically significant (p < 0.05) by t test.