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Reduction of Pbx protein levels in Top2β-/- mice. A–F, Pbx protein expression levels in control and Top2β-/- mice at e11.5. Levels of Pbx1 (p = 0.01) and Pbx3 (p = 0.007) are decreased at all rostrocaudal levels of the spinal cord. G, Quantitation of Hox and Pbx protein levels at e11.5.
