Table 1. Dimeric and trimeric dUTPases induce PICIs from other species encoding SaPIbov1-like Stl repressorsa.
Phage Duts | ||||
---|---|---|---|---|
Dimeric | Trimeric | |||
ϕNM1
S. aureus |
ϕO11
S. aureus |
ϕIPLA6
S. epidermidis |
ϕ11
S. aureus |
|
PICIs | ||||
SaPIbov1 | ++ | ++ | ++ | +++ |
ShoCI794_SEPI | ++ | ++ | ++ | +++ |
ShaCI51-48 | + | + | + | + |
aResults are from 5 independent β-lactamase/Nitrocefin assay experiments, using the dual plasmid system described in the text. Levels of induction were based on the calculated units/ml with the following ranges: (-): no induction, <1 Units/ml; (+): low induction, 1–5 Units/ml; (++): moderate induction, 5–10 Units/ml; (+++): high induction, >10 Units/ml. A 2-way ANOVA with Sidak's multiple comparisons test was performed to compare mean differences within rows. The differences observed among the +,++or +++ samples, compared with the controls or the - samples, were in all cases statistically significant (p<0.05).