Table 1.

Summary of Claustrum Spiny Projection Neuron Responses to Optogenetic Activation of Afferents from Various Cortical Sources

Circuit	% Responsive	% Firing/ Responsive	n
ACC →CL	100	100	14
M1 + S1 →CL	33.3***	0**	9
A1 + V1 →CL	40**	0***	10
S2 + V2 →CL	81.8	0****	11
PtA →CL	0****	N/A	5

For each cortical afferent source to claustrum (CL), the percentage of spiny projection neurons that exhibited PSPs or APs (% Responsive), the percentage of these responsive neurons that fire APs (% Firing/ Responsive), and the total number of neurons recorded are presented (n). The proportion of responsive neurons and responsive neurons that fire APs was compared between ACC afferent stimulation and each other afferent source tested.

Fisher’s exact test:

^**p < 0.01;

^***p < 0.005;

^****p < 0.0001.

S2, secondary somatosensory cortex; V2, secondary visual cortex; PtA, parietal association cortex; N/A, not applicable.