Table 2.
Current alcohol use overall and by type and risk of invasive ductal, invasive lobular, and invasive ducal-lobular breast cancer
| Controls (n = 891) | Ductal cases (n = 905) | Lobular cases (n = 567) | Ductal-lobular cases (n = 489) | ||||
|---|---|---|---|---|---|---|---|
| No.(%) | No.(%) | OR (95% CI)a | No.(%) | OR (95% CI)a | No.(%) | OR (95% CI)a | |
| Alcohol use | |||||||
| Never | 323 (36.3) | 312 (34.5) | 1 [Ref] | 186 (32.8) | 1 [Ref] | 178 (36.4) | 1 [Ref] |
| Former | 126 (14.1) | 123 (13.6) | 1.01 (0.76, 1.36) | 70 (12.4) | 0.97 (0.69, 1.37) | 58 (11.9) | 0.80 (0.56, 1.15) |
| Current | 442 (49.6) | 470 (51.9) | 1.09 (0.89, 1.33) | 311 (54.9) | 1.25 (0.99, 1.58) | 253 (51.7) | 0.99 (0.78, 1.26) |
| Average no. of drinks/week at reference | |||||||
| <4 drinks | 242 (27.2) | 239 (26.4) | 1.01 (0.79, 1.28) | 143 (25.2) | 1.04 (0.79, 1.37) | 126 (25.8) | 0.91 (0.68, 1.21) |
| 4–<7 drinks | 64 (7.2) | 77 (8.5) | 1.22 (0.84, 1.76) | 52 (9.2) | 1.46 (0.97, 2.21) | 36 (7.4) | 0.96 (0.61, 1.51) |
| ≥7 drinks | 136 (15.3) | 154 (17.0) | 1.16 (0.88, 1.54) | 116 (20.5) | 1.52 (1.11, 2.07) | 91 (18.6) | 1.15 (0.83, 1.60) |
| P trend | 0.17 | 0.0005 | 0.40 | ||||
| Average no. of beer/week at reference | |||||||
| <4 | 142 (15.9) | 146 (16.1) | 1.05 (0.79, 1.39) | 101 (17.8) | 1.26 (0.92, 1.73) | 71 (14.5) | 0.86 (0.61, 1.21) |
| 4+ | 15 (1.7) | 21 (2.3) | 1.44 (0.73, 2.85) | 15 (2.7) | 1.78 (0.85, 3.74) | 10 (2.0) | 1.12 (0.49, 2.56) |
| P trend | 0.12 | 0.08 | 0.72 | ||||
| Average no. of red wine/week at reference | |||||||
| <4 | 191 (21.4) | 189 (20.9) | 1.00 (0.77, 1.30) | 128 (22.6) | 1.18 (0.88, 1.58) | 114 (23.3) | 1.02 (0.76, 1.38) |
| 4+ | 73 (8.2) | 64 (7.1) | 0.88 (0.60, 1.27) | 59 (10.4) | 1.43 (0.96, 2.12) | 41 (8.4) | 0.98 (0.64, 1.51) |
| Ptrend | 0.76 | 0.09 | 0.33 | ||||
| Average no. of white wine/week at reference | |||||||
| <4 | 221 (24.8) | 215 (23.8) | 1.00 (0.78, 1.27) | 150 (26.5) | 1.21 (0.91, 1.59) | 120 (24.5) | 0.92 (0.69, 1.24) |
| 4+ | 74 (8.3) | 87 (9.6) | 1.20 (0.85, 1.70) | 56 (9.9) | 1.36 (0.92, 2.01) | 46 (9.4) | 1.06 (0.70, 1.60) |
| P trend | 0.48 | 0.08 | 0.75 | ||||
| Average no. of liquor/week at reference | |||||||
| <4 | 245 (27.5) | 225 (24.9) | 0.93 (0.73, 1.18) | 154 (27.2) | 1.10 (0.83, 1.44) | 113 (23.1) | 0.79 (0.59, 1.06) |
| 4+ | 35 (3.9) | 56 (6.2) | 1.66 (1.06, 2.61) | 40 (7.1) | 2.05 (1.25, 3.34) | 27 (5.5) | 1.34 (0.79, 2.30) |
| P trend | 0.02 | 0.0008 | 0.07 | ||||
aOR (95% CI) adjusted for age, reference year, and county of reference