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. 2018 Jan 23;13(1):e0191356. doi: 10.1371/journal.pone.0191356

Fig 3. Effects of WPCD on BM-DCs function through TLR4-mediated pathway.

Fig 3

After pretreatment with 5 μM of TAK-242 for 1 h, BM-DCs were treated with 100 ng/mL LPS or 100 and 200 μg/mL WPCD for 12 h in the presence or absence of Golgi Stop. Then CD40, CD86, TNF-a and IL-12 expressions were detected by FACs or ELISA. The MFI values of CD40 (A) and CD86 (B), the yields of TNF-a (C), and IL-12 (D) were shown. Data represent mean ± SD (n = 3) from 3 independent experiments.*P < 0.05, **P < 0.01, ***P < 0.001 compared with the untreated DCs group.