Effect of paclitaxel (PTX) and/or MG132 on the migration and invasion of breast cancer cells. Wound healing assays show that PTX and/or MG132 treatment decreased the ability of MCF-7 and EO771 cells to migrate in a concentration-dependent manner (A, B), and reduced the invasive potential of MCF-7 and EO771 cells (C, D). Data are expressed as means ± standard deviation of 3 independent experiments. P0.1, PTX 0.1 μM; P0.5, PTX 0.5 μM; M0.25, MG132 0.25 μM; M0.5, MG132 0.5 μM; P + M, PTX 0.1 μM and MG132 0.25 μM; * p<0.05 vs. single-treatment and control (ctrl) groups.