Table 5.
Pre‐treatment IC50 values for each neuraminidase inhibitor used in the 2010–2011 season
| IC50 before starting therapy, nm | A(H1N1) pdm09 (a) | A(H3N2) (b) | B (c) | P value between | ||
|---|---|---|---|---|---|---|
| (a) and (b) | (b) and (c) | (a) and (c) | ||||
| Oseltamivir | 0·97 ± 0·48 (31) | 0·74 ± 0·13 (9) | 44·5 ± 13·6 (11) | <0·05 | <0·001 | <0·001 |
| Zanamivir | 0·86 ± 0·32 (31) | 1·94 ± 0·43 (9) | 12·3 ± 4·0 (11) | <0·001 | <0·001 | <0·001 |
| Laninamivir | 1·77 ± 0·78 (31) | 3·9 ± 1·6 (9) | 21·3 ± 6·9 (11) | <0·001 | <0·001 | <0·001 |
*Duration of fever after the first dose () number of patients.