Table 3.
In‐hospital case fatality risk (CFR) among diabetic (grouped type 1 and type 2) and non‐diabetic patients hospitalized with confirmed 2009 A(H1N1)pdm09 in Spain according to study variables
| Patients with diabetes | Non‐diabetics patients | IRR (95%CI)* | |||
|---|---|---|---|---|---|
| n | CFR % 95% CI | n | CFR % 95% CI | ||
| Age groups (years) | |||||
| <18 | 0 | 0 (–) | 26 | 0·8 (0·5–1·13) | NA |
| 18–30 | 0 | 0 (–) | 33 | 1·8 (1·1–2·4) | NA |
| 31–45 | 6 | 4·4 (0·9–7·8) | 56 | 2·3 (1·6–2·8) | 1·96 (0·83–4·65) |
| 46–60 | 11 | 3·1 (1·3–4·9) | 63 | 3·4 (2·6–4·2) | 0·90 (0·47–1·74) |
| 61–75 | 15 | 4·4 (2·2–6·6) | 38 | 4·82 (3·3–6·3) | 0·92 (0·50–1·70) |
| 76 and over | 6 | 4·5 (0·9–8·1) | 28 | 9·3 (6–12·5) | 0·46 (0·18–1·15) |
| Sex | |||||
| Men | 20 | 3·7 (2·1–5·3) | 141 | 2·7 (2·2–3·1) | 1·39 (0·87–2·24) |
| Women | 18 | 3·6 (1·9–5·2) | 103 | 2·0 (1·6–2·3) | 1·85 (1·11–3·09) |
| Pregnancy | 0 | 0 (0–0) | 7 | 1·0 (0·26–1·7) | NA |
| No chronic disease* | 9 | 2·7 (0·9–4·4) | 50 | 0·9 (0·6–1·13) | 3·08 (1·50–6·33) |
| Chronic cardiovascular disease | 4 | 4·76 (0·2–9·3) | 14 | 9·3 (4·6–13·9) | 0·48 (0·15–1·53) |
| Chronic respiratory disease (asthma not included) | 5 | 2·3 (0·3–4·3) | 36 | 3·7 (2·5–4·9) | 0·61 |
| Asthma | 1 | 0·9 (0·0–2·6) | 14 | 0·8 (0·4–1·2) | 1·06 (0·13–8·14) |
| Obesity | 12 | 4·7 (2·1–7·3) | 37 | 5·1 (3·5–6·7) | 0·91 (0·47–1·77) |
| Endocrine disease | 4 | 5·4 (0·2–10·5) | 15 | 3·7 (1·8–5·4) | 1·50 (0·48–4·66) |
| Cancer | 4 | 8·7 (0·5–16·8) | 54 | 11·6 (8·6–14·4) | 0·73 (0·25–2·10) |
| Hematological disease** | 7 | 10·4 (3·1–17·7) | 75 | 9·1 (7·1–11·0) | 1·17 (0·51–2·64) |
| Epilepsy | 1 | 7·1 (0·0–20·6) | 14 | 5·8 (2·8–8·6) | 1·25 (0·15–10·32) |
| Diseases of the CNS | 0 | 0 (–) | 15 | 15·9 (8·5–23·3) | NA |
| Chronic liver disease | 0 | 0 (–) | 8 | 26·6 (10·8–42·49 | NA |
| Chronic renal disease | 7 | 6·5 (1·8–11·2) | 21 | 7·5 (4·4–10·5) | 0·86 (0·35–2·09) |
CFR In‐hospital case fatality risk.
*No chronic disease excludes all listed diseases.
**Incidence rate ratios and 95% CI comparing non‐diabetic (ref category) versus diabetic patients using Poisson regression.