Figure 2.

miR-372 inhibits proliferation and induces apoptosis in MCF-7 cells. Relative miR-372 levels in MCF-7 cells when transfected with (A) miR-372 mimics (miR-372) or (B) miR-372 inhibitors (anti-miR-372), as detected by reverse transcription-quantitative polymerase chain reaction. Proliferation of MCF-7 cells transfected with miR-372 (C) inhibitors and (D) mimics, as measured by MTT assay. Apoptosis rate of transfected MCF-7 cells transfected with miR-372 (E) inhibitors and (F) mimics, as analyzed by flow cytometry. Data are presented as the mean ± standard deviation of three independent experiments. *P<0.05. miR-372, microRNA-372; OD, optical density.