Table II.

Target gene-associated pathways.

Pathway ID	Definition	P-value	Selection counts	Size	Enrichment score	Genes
hsa04150	mTOR signaling pathway	0.04	20	6,890	1.37	AKT1, AKT2, EIF4E2, IKBKB, IRS1, MAPK3, PDPK1, PIK3CD, PIK3R5, PRKCA, PRKCB, RPS6KA2, RPS6KB2, RRAGA, STK11, STRADA, TNF, TSC2, ULK1, ULK3
hsa04923	Regulation of lipolysis in adipocytes	0.033	4	6,890	1.474	PIK3R3, PLA2G16, PRKG1, TSHR
hsa04012	ErbB signaling pathway	0.02	29	6,890	1.77	AKT1, AKT2, ARAF, CAMK2G, CDKN1A, CDKN1B, CRK, CRKL, ELK1, GRB2, GSK3B, HRAS, MAP2K7, MAPK3, MYC, NCK1, NCK2, PAK2, PIK3CD, PIK3R5, PLCG1, PRKCA, PRKCB, RPS6KB2, SHC1, SRC, STAT5A, STAT5B, TGFA
hsa04621	NOD-like receptor signaling pathway	0.005	22	6,890	2.252	CARD6, CARD8, CARD9, CASP5, CASP8, CHUK, CXCL1, IKBKB, MAPK13, MAPK14, MAPK3, MEFV, NFKB1, NLRP1, NLRP3, NOD1, NOD2, PSTPIP1, PYCARD, RELA, SUGT1, TNF
hsa05133	Pertussis	0.02	5	6,890	1.65	C4BPA, C5, CASP7, IL10, IL12A
hsa04330	Notch signaling pathway	0.001	21	6,890	2.96	APH1A, CREBBP, CTBP2, DTX1, DTX3, DVL1, DVL2, DVL3, HDAC1, HDAC2, JAG2, KAT2A, LFNG, MFNG, NCOR2, NCSTN, NOTCH1, NOTCH2, NUMB, PSENEN, RFNG