Table VII.

IL-6, TNF-α, CRP, NO, eNOS and iNOS in rat endotheliocytes prior to and following CIH induction.

		CIH induction time
Factor	Groups	0 h	1 h	2 h	3 h
IL-6, ng/ml	CIH	0.72±0.08	1.24±0.09a	1.85±0.05a,b	2.34±0.05a–c
	Control	0.65±0.04	0.79±0.08	0.84±0.04	0.95±0.02
TNF-α, pg/ml	CIH	0.83±0.07	1.16±0.06a,b	2.05±0.08a–c	2.18±0.06a–c
	Control	0.62±0.03	0.68±0.09	0.54±0.05	0.86±0.06
CRP, µg/ml	CIH	0.79±0.03	0.95±0.08a,b	1.04±0.07a,b	1.27±0.05a–d
	Control	0.82±0.05	0.80±0.08	0.72±0.05	0.66±0.03
NO, µM	CIH	3.54±0.26	2.88±0.14a,b	1.60±0.22a–c	1.04±0.19a–d
	Control	3.92±0.33	4.25±0.27	3.51±0.22	4.07±0.30
eNOS, U/ml	CIH	2.38±0.09	0.82±0.04a,b	0.46±0.05a–c	0.30±0.03a–d
	Control	2.06±0.05	1.73±0.08	1.80±0.06	1.62±0.04
iNOS, U/ml	CIH	0.18±0.05	0.26±0.07a	0.38±0.04a,b	0.40±0.05a,b
	Control	0.09±0.01	0.07±0.03	0.11±0.02	0.08±0.02

^aP<0.05 vs. control

^bP<0.05 vs. CIH-0 h

^cP<0.05 vs. CIH-1 h

^dP<0.05 vs. CIH-2 h. CIH, chronic intermittent hypoxia; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; CRP, C-reactive protein; NO, nitric oxide; eNOS, endothelial nitric oxide synthase; iNOS, inducible nitric oxide synthase.