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Inhibition of transforming growth factor-β signaling promotes the secretion of HGF in fibroblasts. (A) MLg cells were cultured in control condition or with 10 µM SB431542 for 48 h. (B) Quantitative analysis of the number of MLg cells. (C) Reverse transcription-quantitative polymerase chain reaction analysis was performed to quantify Hgf gene expression. Scale bars, 200 µm. Data are expressed as the mean ± standard error of the mean. *P<0.05 as indicated. HGF, hepatocyte growth factor.
