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Metformin therapy accelerates wound closure in db/db mice. A dorsal skin wound was created via a 6-mm circular punch biopsy and digital images of the wound were captured every 2 days until day 14. (A) Representative images of wound healing. (B) Metformin therapy accelerated wound closure compared with control in db/db mice. *P<0.05 vs. Con; #P<0.05 vs. db/db. Values are expressed as the mean ± standard error of the mean (n=5 mice/group). Con, control; Met, metformin.
