Table I.
Genotype and allele frequencies of the 27-bp eNOS VNTR analyzed in 125 JIA patients and 221 healthy controls.
| Variables | JIA (N=125) | Controls (N=221) | P-value | OR (95% CI) |
|---|---|---|---|---|
| Genotypes | ||||
| b/b | 60 (48%) | 162 (73.30%) | ||
| b/a | 47 (37.6%) | 49 (22.17%) | 0.05 | 0.4 (0.16–1.02) |
| a/a | 19 (15.2%) | 8 (3.63%) | <0.0001 | 0.15 (0.065–0.37) |
| Alleles | ||||
| B | 167 (66.8%) | 373 (84.39%) | ||
| A | 85 (33.2%) | 65 (14.71%) | <0.0001 | 0.34 (0.23–0.49) |
eNOS, endothelial nitric oxide synthase; JIA, juvenile idiopathic arthritis; OR, odds ratio; CI, confidence interval. Bold, statistically significant.