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Caudatin hinders in vivo angiogenesis. Caudatin inhibited the tumor volume (A) and tumor weight (B). (C) Caudatin suppressed the expressions of phosphorylated AKT and FAK in tumor xenograft. (D) Effects of caudatin on Ki-67, VEGF and CD-34 expression in vivo. Different letters on bars are statistically different at P<0.05 level when compared between any two groups. AKT, protein kinase; FAK, focal adhesion kinase; VEGF, vascular endothelial growth factor.
