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. 2017 Oct 17;16(6):9347–9354. doi: 10.3892/mmr.2017.7795

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Copyright: © Cong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — mRNA expression of 15-HPGD, PGE2 and miRs targeting 15-HPGD. Targeting miRs were identified using TargetScan and analyzed via reverse transcription-quantitative polymerase chain reaction. miRNA218 and PGE2 expression were significantly higher compared with undifferentiated cells at baseline. Following 10 days of differentiation, 15-HPGD was significantly increased compared with undifferentiated cells. *P<0.05 vs. Undifferentiated cells. miR, microRNA; 15-HPGD, 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; PGE2, prostaglandin E2; undiff, undifferentiated.