Table III.
Factor | PGE2 | miR-218 | HPGD gene | PTGES | PLA2G6 | COX1 | HPGD protein | mPGES | PLA | COX |
---|---|---|---|---|---|---|---|---|---|---|
PGE2 | 1.000 | 0.989 | −0.949 | 0.099 | −0.547 | 0.245 | −0.940 | −0.774 | −0.254 | 0.245 |
miR-218 | 0.989 | 1.000 | −0.974 | 0.023 | −0.547 | 0.209 | −0.970 | −0.784 | −0.243 | 0.209 |
HPGD gene | −0.949 | −0.974 | 1.000 | 0.125 | 0.448 | −0.216 | 0.999 | 0.764 | 0.253 | −0.216 |
PTGES | 0.099 | 0.023 | 0.125 | 1.000 | −0.246 | −0.154 | 0.141 | −0.341 | 0.366 | −0.154 |
PLA2G6 | −0.547 | −0.547 | 0.448 | −0.246 | 1.000 | 0.248 | 0.448 | 0.467 | −0.005 | 0.248 |
COX1 | 0.245 | 0.209 | −0.216 | −0.154 | 0.248 | 1.000 | −0.217 | −0.240 | 0.041 | 1.000 |
HPGD protein | −0.940 | −0.970 | 0.999 | 0.141 | 0.448 | −0.217 | 1.000 | 0.772 | 0.227 | −0.217 |
mPGES | −0.774 | −0.784 | 0.764 | −0.341 | 0.467 | −0.240 | 0.772 | 1.000 | −0.109 | −0.240 |
PLA | −0.254 | −0.243 | 0.253 | 0.366 | −0.005 | 0.041 | 0.227 | −0.109 | 1.000 | 0.041 |
COX | 0.245 | 0.209 | −0.216 | −0.154 | 0.248 | 1.000 | −0.217 | −0.240 | 0.041 | 1.000 |
PGE2, prostaglandin E2; miR, microRNA; HPGD, 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; PTGES, prostaglandin E synthase; PLA2G6, 85/88 kDa calcium-independent phospholipase A2; COX1, cyclooxygenase 1; mPGES, microsomal prostaglandin E synthase 1; PLA, phospholipase A2.