Figure 2.

Effect of miR-137 mimic on HepG2 cells. (A) RT-qPCR was used to examine the miR-137 expression in liver cancer cell lines compared with normal liver epithelial THLE-3 cells. **P<0.01 vs. THLE-3. (B) HepG2 cells were transfected with miR-137 mimic or miR-NC and RT-qPCR was used to examine the miR-137 expression. **P<0.01 vs. miR-NC. (C) MTT assay, (D) Transwell assay (magnification, ×400) and (E) wound healing assay (magnification, ×40) were conducted to examine the cell proliferation, invasion and migration of HepG2 cells, respectively. **P<0.01 vs. miR-NC. RT-qPCR, reverse transcription-quantitative polymerase chain reaction; miR, microRNA; miR-NC, negative control scramble miR; OD, optical density.