Table 1.
Clinical and laboratory characteristics of the p.P50T/AKT2 noncarriers and carriers who participated in the METSIM PET studies
| Variable | Noncarriers (N = 25) | Carriers (N = 20) | P value |
|---|---|---|---|
| Age, years | 63.9 ± 4.8 | 61.9 ± 6.3 | 0.23 |
| Height, cm | 176.9 ± 5.3 | 174.2 ± 5.5 | 0.10 |
| Weight, kg | 87.4 ± 10.2 | 86.1 ± 11.6.2 | 0.70 |
| BMI, kg/m2 | 28.1 ± 3.4 | 28.7 ± 3.4 | 0.60 |
| Waist, cm | 100.7 ± 8.9 | 100.3 ± 8.7 | 0.88 |
| Fat mass, % | 29.0 ± 7.0 | 28.0 ± 7.0 | 0.60 |
| Systolic blood pressure, mmHg | 133.8 ± 14.1 | 137.3 ± 15.9 | 0.44 |
| Diastolic blood pressure, mmHg | 86.4 ± 10.1 | 86.6 ± 8.5 | 0.94 |
| Fasting plasma glucose, mmol/L | 6.0 ± 6.5 | 6.1 ± 0.3 | 0.28 |
| Fasting insulin, mU/L | 9.4 ± 5.6 | 17.8 ± 10.2 | 0.003 |
| LDL cholesterol, mmol/L | 3.30 ± 0.96 | 2.92 ± 1.09 | 0.21 |
| HDL cholesterol, mmol/L | 1.51 ± 0.38 | 1.33 ± 0.37 | 0.12 |
| Total triglycerides, mmol/L | 1.12 ± 0.50 | 1.48 ± 1.04 | 0.26 |
| Alanine transferase, units/L | 29.7 ± 13.6 | 32.6 ± 17.8 | 0.58 |
| Creatinine, µmol/L | 85.3 ± 10.5 | 85.5 ± 12.6 | 0.96 |
Data are mean ± SD. Total triglycerides and alanine transferase were log-transformed to calculate P value.