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. 2017 Nov 14;17(1):1445–1452. doi: 10.3892/mmr.2017.8055

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — LMK-235 combined with mineralizing medium increases the mRNA expression of odontoblast-specific factors in DPCs. mRNA expression levels of (A) DSPP, (B) ALP, (C) Runx2 and (D) OCN in DPCs following treatment with LMK-235 for 7, 14 and 21 days. Data are presented as the mean ± standard deviation. *P<0.05, **P<0.01, ***P<0.001. DPCs, dental pulp cells; ALP, alkaline phosphatase; DSPP, dentin sialophosphoprotein; Runx2, runt-related transcription factor 2; MI, mineralized inductive; OCN, osteocalcin.