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. 2017 Nov 15;17(1):1625–1632. doi: 10.3892/mmr.2017.8082

Figure 3.

Figure 3.

NF-H immunohistochemistry in the hippocampal subregions of the (A) control and SCO-treated mice following (B) 1, (C) 2 and (D) 4 weeks. NF-H immunoreactive cells (indicated by arrows) increased in the CA1-3 regions (Bb and Bc) 1 week following scopolamine treatment. A total of 2 and 4 weeks following SCO treatment (C and D, a-d), NF-H immunoreactivity decreased in all hippocampal subregions, in particular, in the stratum pyramidale (indicated by SP and an asterisk) of the (Dc) CA2/3 region 4 weeks following SCO treatment. Scale bars=800 µm (Aa-Da), 50 µm (Ab-Db) and 100 µm (Ac-Dc and Ad-Dd). CA, cornus ammonis; DG, dentate gyrus; GCL, granule cell layer; Mol, molecular layer; PoL, polymorphic layer; SO, stratum oriens; SR, stratum radiatum; SP, stratum pyramidale; NF-H, neurofilament-200 kDa; SCO, scopolamine.