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. 2017 Nov 15;17(1):1753–1761. doi: 10.3892/mmr.2017.8081

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Effect of prehypertensive losartan therapy on the expression of AT1aR, AT1bR and ATRAP in the adipose tissue of high-fat-fed SHRs at 26 weeks of age. (A) The mRNA expression levels of AT1aR, AT1bR and ATRAP, (B) the protein expression level of AT1R, (C) the protein expression level of ATRAP and (D) the protein ratio of AT1R to ATRAP were measured. *P<0.05 vs. SC; #P<0.05 vs. HF. The data are presented as the mean ± standard deviation. n=8. AT1aR, angiotensin II type 1 receptor subtype a; ATRAP, AT1R-associated protein; SHRs, spontaneously hypertensive rats; SC, standard chow-fed SHRs; HF, high-fat-fed SHRs; SC-Los, losartan-treated SHRs on standard chow; HF-Los, losartan-treated SHRs on high-fat diet.