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. 2017 Nov 14;17(1):1775–1781. doi: 10.3892/mmr.2017.8054

Table I.

Treatment of the rats in the different groups.

Treatment 1 Treatment 2


Group Reagent Description Reagent Description
Ctrl Physiological saline 10 days prior to injection; oral administration; equal volume to matrine Sodium citrate buffer (pH 4.5) Equal volume to STZ injection; single intraperitoneal injection
DbCM Physiological saline 10 days before injection; oral administration; equal volume to matrine STZ (dissolved in sodium citrate buffer, pH 4.5) 65 mg/kg body weight; single intraperitoneal injection
Mat Matrine 10 days before injection; oral administration; 200 mg/kg/day for 10 consecutive days Sodium citrate buffer, pH 4.5 Equal volume to STZ injection; single intraperitoneal injection
DbCM+Mat Matrine 10 days prior to injection; oral administration; 200 mg/kg/day for 10 consecutive days STZ (dissolved in sodium citrate buffer with pH 4.5) 65 mg/kg body weight; single intraperitoneal injection

Ctrl, control; Mat, matrine; STZ, streptozotocin; DbCM, diabetic cardiomyopathy.