Figure 5.

Extent of autophagic activation in the brain cortex following SAH injury. (A) Expression of autophagy-related proteins Beclin-1 and LC3-I/II was observed using western blotting. (B) The expression of Beclin-1 was increased in rRIPostC compared with other groups. dRIPostC and rRIPostC increased the (C) LC3-I and (D) LC3-II level. Data are presented as the mean ± standard deviation. n=4. *P<0.05 vs. other groups, ^&P<0.05 vs. sham SAH and eRIPostC groups. SAH, subarachnoid hemorrhage; eRIPostC, early remote ischemic post-conditioning; dRIPostC, delayed RIPostC; rRIPostC, repeated RIPostC; LC3, light chain 3.