Table II.
Characteristic | Negative control | Vehicle control | Experiment |
---|---|---|---|
HW/BW | 0.28±0.03 | 0.34±0.03a | 0.30±0.01b |
LVEDd (mm) | 4.93±0.35 | 7.00±0.34a | 5.48±0.22a,c |
LVEDs (mm) | 2.82±0.86 | 5.02±0.31a | 3.02±0.36c |
IVS (mm) | 2.16±0.20 | 2.12±0.19 | 2.10±0.20 |
LVWP (mm) | 2.34±0.11 | 2.12±0.26 | 2.22±0.15 |
LVFS | 0.47±0.05 | 0.28±0.02a | 0.40±0.03c |
P 0.01 vs. normal
P<0.05 vs. control
P<0.01 vs. control. HW/BW, heart weight/body weight; LVEDd, left ventricular dimension in end diastole; LVEDs, left ventricular dimension in end systole; IVS, interventricular septal thickness; LVPW, left ventricular posterior wall thickness; LVFS, left ventricular fractional shortening; DCM, dilated cardiomyopathy; Negative control, age-matched untreated rats; Vehicle control, DCM rats treated with vehicle; Experiment, DCM rats treated with HuMSCs.