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. 2017 Oct 24;17(1):79–86. doi: 10.3892/mmr.2017.7859

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Copyright: © He et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Representative images showing CA9 (a marker for tumor hypoxia) immunohistochemistry staining in Lewis lung cancer tumors following treatment with rh-ES or NS for days 2, 4, 6 and 9. The positive CA9 signals were located on the cell membrane and had a color of brown. Magnification, ×400. CA9, carbonic anhydrase 9; rh-ES, recombinant human endostatin; NS, normal saline.