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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Surgery. 2017 Nov 22;163(2):336–342. doi: 10.1016/j.surg.2017.09.030

Fig. 3. Intratumoral injection of CF189 in MDA-MB-468 xenografts effectively reduces relative tumor size at doses as low as 103 PFU per tumor compared to control without significant toxicity.

Fig. 3

(A) Tumors were injected with PBS (control), 103 PFU per tumor, 104 PFU per tumor or 105 PFU per tumor at an initial tumor volume of approximately 100–150 mm3. (B) No significant reductions in relative body weight were observed in nude mice treated with intratumoral CF189 injection compared to PBS-injected controls.