Table 1.
Clinical characteristics of the study cohort (n = 6712)
| Baseline Characteristics | Mean (Median when specified) (SD or %) |
|---|---|
| Age (years) | 62.2 ± 10.2 |
| Female (%) | 52.8 |
| Race/Ethnicity (%) | |
| Whites | 32.3 |
| Chinese | 11.9 |
| African American | 27.6 |
| Hispanics | 22.2 |
| Body Mass Index (BMI) (kg/m2) | 28.3 ± 5.5 |
| Cholesterol (mg/dL) | |
| Total | 194.2 ± 35.7 |
| Low density lipoprotein (LDL) | 117.2 ± 31.4 |
| High density lipoprotein (HDL) | 51.0 ± 14.8 |
| Triglycerides | 131.6 ± 89.0 |
| Blood Pressure (mm/Hg) | |
| Systolic | 126.6 ± 21.5 |
| Diastolic | 71.9 ± 10.3 |
| Cigarette Smoking Status (%) | |
| Never | 50.3 |
| Former | 36.7 |
| Current | 13.0 |
| Diabetes Mellitus (%) | 12.7 |
| Blood Pressure Medication use (%) | 33.2 |
| Statin use (%) | 14.8 |
| Aspirin Use (%) | 20.0 |
| Original Framingham Stroke Risk Score (Original FSRS) | 5.9 ± 1.2 |
| Revised Framingham Stroke Risk Score (Revised FSRS) | 4.7 ± 5.3 |
| Pooled Cohort Equation | 13.2 ± 13.1 |
| Coronary Artery Calcium (CAC) Score (Agatston Units)¥ | |
| Median (IQR) | 0.0 (0.0 – 86.2) |
| Carotid Intima Media Thickness (CIMT) (mm) | |
| Median (IQR) | 0.8 (0.7 – 1.0) |
| High Sensitivity C Reactive Protein (CRP) (mg/L) | |
| Median (IQR) | 3.8 (0.8 – 4.3) |
| Ankle Brachial Index (ABI) | 1.1 (1.1 – 1.2) |
| Median (IQR) | |
| Family history of stroke (First degree relative) (%) | 32.6 |
| Total number of strokes | 231 (3.5%) |
*
IQR: Interquartile range, (Q1 to Q3, 25th to 75th percentile)
¥
CAC range is significantly skewed given that median CAC score is 0.