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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: J Immunol. 2017 Dec 29;200(3):1133–1145. doi: 10.4049/jimmunol.1701272

Fig. 2. CD8+ T cells with a TRM phenotype can form in the salivary glands of naïve mice and mice latently infected with MCMV.

Fig. 2

(A) Schematic of the experimental design. Naïve mice or mice that had been infected (i.p.) for 9 weeks with wild-type MCMV (lacking Ova) were seeded with 3×106 in vitro activated OT-Is and sacrificed 2 weeks after transfer. B) Absolute number of OT-Is from the parenchyma of the salivary gland (SG), lungs (LG), kidneys (KDN) and from the overall CD8β+ population of the spleen (SPL). (C) Frequency of CD103 and CD69 expression on OT-Is from the parenchyma of the SG, LG and KDN. Data combined from 2 independent experiments (n=7). (D) Concatenated FACS plots from a representative experiment with frequency mean ± SEM values considering all the experiments. An unpaired t-test was used to test for statistical significance.