Table 2.
Outcomes by Clinical Trajectory
| Outcomes | RAP (n=66) | CCI (n=71) | p-value |
|---|---|---|---|
| Hospital mortality, n (%) | 0 (0) | 11 (15.5) | 0.0007 |
| ICU LOS, median (25th, 75th) | 6 (3, 9) | 22 (16, 34) | <0.001 |
| Hospital LOS, median (25th, 75th) | 10 (7, 17) | 29 (19, 44) | <0.001 |
| Ventilator days, median (25th, 75th) | 3 (2, 5) | 15.5 (7.5, 22.5) | <0.001 |
| Maximum SOFA score*, median (25th, 75th) | 5 (3, 8) | 10 (7, 12) | <0.001 |
| Multiple organ failure**, n (%) | 26 (30.6) | 36 (70) | <0.001 |
| ARDS | 0 (0) | 6 (8.5) | 0.03 |
| AKI, n (%) | 31 (47) | 49 (69) | 0.01 |
| AKI KDIGO Stage, n (%) | 0.07 | ||
| 1 | 17 (25.8) | 23 (32.4) | |
| 2 | 9 (13.6) | 14 (19.7) | |
| 3 | 5 (7.6) | 12 (16.9) | |
| ESRD | 2 (3) | 0 (0) | |
| Discharge disposition, n (%) | |||
| “Good” Disposition | 47 (71.2) | 14 (19.7) | <0.001 |
| Home | 29 (43.9) | 0 (0) | |
| Rehab | 14 (21.2) | 6 (8.5) | |
| Home healthcare services | 4 (6.1) | 8 (11.3) | |
| “Poor” Disposition | 19 (28.8) | 57 (80.3) | <0.001 |
| Long Term Acute Care facility | 2 (3) | 23 (32.4) | |
| Skilled Nursing facility | 17 (25.8) | 7 (9.9) | |
| Another Hospital | 0 (0) | 12 (16.9) | |
| Hospice | 0 (0) | 4 (5.6) | |
| Death | 0 (0) | 11 (15.5) |
Definition of Abbreviations: RAP, rapid recovery; CCI, chronic critical illness; BMI, body mass index; LOS, length of stay; SOFA, sequential organ failure assessment; ARDS, acute respiratory distress syndrome; AKI, acute kidney injury; KDIGO, Kidney disease improving global outcomes staging; ESRD, end-stage renal disease; UTI, urinary tract infection.
*
SOFA score, defined as a composite score of six different organ systems (respiratory, cardiovascular, hepatic, coagulation, renal, and neurological systems) used to determine the extent of a patient’s organ dysfunction.
**
Multiple organ failure, defined as SOFA component score ≥3 in at least two organs systems.