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. 2018 Jan 19;11:6. doi: 10.3389/fnmol.2018.00006

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Copyright © 2018 Cao, Hua, Xiong, Zhu, Zhang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Triclosan (TCS) causes prolongation of diestrus. (A) Body weights (g) of mice. (B) Representative estrous cycles before and after TCS-exposure for 50 days. Connected dots indicate the time of diestrus (D), proestrus (P) or estrus (E), respectively. *: persistent diestrus; ↑: loss of proestrus. (C) Bar graph shows the mean time (day) of one estrous cycle within TCS-exposure. **P < 0.01 vs. control mice (one-way ANOVA). (D) Bars represent the mean length (day) of diestrus (D), proestrus (P), or estrus (E), respectively, per estrous cycle. **P < 0.01 vs. control mice (one-way ANOVA).