Figure 3.

The selectin family. Selectins are a family of three carbohydrate-binding proteins: P-selectin, expressed on activated platelets and endothelial cells, E-selectin expressed on activated endothelial cells, and L-selectin expressed on leukocytes. The figure represents the five domains shared by selectins: C-type lectin domain, epidermal growth factor-like domain (EGF), a varying number of short consensus repeats having homology to complement regulatory proteins, a transmembrane region, and a cytoplasmatic domain.