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. 2018 Jan 19;10:455. doi: 10.3389/fnmol.2017.00455

Table 1.

A list of abbreviations and the functions of iron related proteins.

Abbreviation Function
Divalent metal transporter 1 DMT1 Cellular iron importer responsible for ferrous iron uptake
Ferroportin1 FPN1 Cellular iron exporter responsible for ferrous iron release
Ceruloplasmin Cp A ferroxidase mediating oxidization of Fe2+ to Fe3+ and promoting FPN1-mediated iron release
Transferrin/transferrin receptor 1 Tf/TfR1 A major pathway for Fe3+ ions acquisition to cells by a receptor-mediated pathway
Lactoferrin/lactoferrin receptor Lf/LfR Transfers Fe3+ ions to cells by a receptor-mediated pathway
Ferritin Ferritin Intracellular iron-storage protein, keeping iron in a non-toxic form
Hepcidin Hepcidin A circulating peptide that binds to FPN1, mediating degradation of FPN1