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. 2018 Jan 23;8:1423. doi: 10.1038/s41598-018-19675-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The time difference between epileptiform events recorded in the area of injection (red line) and other brain areas after injection of kainic acid in 3 different rats (A–C) [numbers in square brackets are identical with the rat number in the Table 2]. The average of the first 10 epileptiform events from the seizure onset normalized by amplitude are presented in each graph. The areas which show epileptiform events are indicated on the left of each graph and color matched to the lines in the graph. The numbers indicate the physical distance between the recorded site and the injection site in mm. The minor division on the scale is 1ms. Shaded lines indicate SD Abbreviations are the same as on the Fig. 2D. Correlation of multiunit discharges and LFP during seizure development after kainic acid injection. The top lines are LFPs for each recorded brain area and below are perievent histograms referenced to the peak of LFP recorded in the injection area.