Figure 1.

Similar gross morphology of the brain and body weights between wild-type and Kirrel3^−/− mice. (a) Western blots of olfactory, hippocampal, and cerebellar homogenates from wild-type (WT) and Kirrel3^−/− (KO) mice probed with a Kirrel3 antibody. A single band (100 kDa: arrow) was detected in the olfactory bulb (Ob), hippocampus (Hip), and cerebellum (Cb) in wild-type mice, but not in Kirrel3^−/− mice. β-actin was used as the loading control. Full-length blots are shown in Supplementary Fig. S2a. (b) Gross morphology of adult brain from wild-type (WT) and Kirrel3^−/− (KO) mice. There were no differences between genotypes. Scale bar, 5 mm. (c) Body weights of wild-type (WT) and Kirrel3^−/− (KO) mice throughout development. There were no differences between genotypes (n = 5–14, at each age; p > 0.05 at all ages, one-way ANOVA). Error bars indicate SEM.