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. 2018 Jan 23;3:5. doi: 10.1038/s41541-017-0039-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — 17D-204 is more sensitive to IFN-γ-induced antiviral states than wild-type strain Angola71 in myeloid cells. Indicated cell types were treated with designated IFN 12 h prior to infection with 17D-204 or Angola71 at MOI = 0.1. (n = 6, 1 out of 3 independent experiments is shown.) At 48 hpi, supernatants were harvested and infectious virus particles were quantified by focus forming assay on Vero cells. a–d Bone marrow-derived macrophages and e, f mouse embryonic fibroblasts from various strains of mice. Foci titers (FFU/mL) were normalized to that of untreated cells, and data are presented in mean percentage ± SD. Corresponding foci titers are available in Fig. S5. (*p < 0.05, **p < 0.01, ***p < 0.005, ****p < 0.001; multiple t-test, corrected by Holm–Sidak method)