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. 2018 Jan 23;8:1439. doi: 10.1038/s41598-018-19949-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Begg’s funnel plot analyses to assess the publication bias between MGMT methylation and different NSCLC clinicopathological characteristics; (A) Overall funnel plot from pooled 20 studies, (B) Funnel plot based on age, (C) Funnel plot based on sex status, (D) Funnel plot based on smoking status, (E) Funnel plot based on pathological types, (F) Funnel plot based on differentiation status, (G) Funnel plot based on clinical stage status, and (H) Funnel plot based on NSCLC overall survival.