Table 2.
Follow-Up Data on Treatment From Baseline Through 24 Months of cART for Young and Older Patients Initiating Treatment
| Variable | Total | Young (15–49 Years) | Older (≥50 Years) | P Value |
|---|---|---|---|---|
| Days on HIV care, median (IQR) | 1541 (1051–2051) | 1547 (1056–2052) | 1468 (1020–2004) | .01 |
| Days on cART, median (IQR) | 1610 (1092–2112) | 1614 (1093–2114) | 1586 (1064–2081) | .10 |
| Median CD4+ Cell Increase From Baseline (IQR), Cells/mm3 | ||||
| Month 6 | 110 (25–200) | 112 (27–202) | 94 (2–179) | .0002 |
| Month 12 | 149 (55–254) | 151 (56–256) | 132 (43–232) | .0005 |
| Month 18 | 165 (39–284) | 116 (40–286) | 153 (30–265) | .03 |
| Month 24 | 182 (21–312) | 185 (24–318) | 151 (0–266) | <.001 |
| Viral Suppression (% <400 copies/mL) | ||||
| Month 6 | 4807 (70.5) | 4424 (70.2) | 383 (73.9) | .04 |
| Month 12 | 4992 (69.1) | 4596 (68.9) | 396 (71.6) | .13 |
| Month 18 | 4451 (68.8) | 4100 (68.7) | 351 (70.8) | .24 |
| Month 24 | 4200 (70.0) | 3867 (69.6) | 333 (74.8) | .005 |
| Number of Treatment Gaps | .47 | |||
| None | 7330 (87.8) | 6760 (87.7) | 570 (88.6) | |
| ≥1 gap | 1022 (12.2) | 949 (12.3) | 73 (11.4) | |
| ≥95% adherence | 4898 (58.6) | 4523 (58.7) | 375 (58.3) | .86 |
| Drug Switch at 6 Month, n (%) | .59 | |||
| Yes | 18 (0.2) | 17 (0.2) | 1 (0.2) | |
| No | 8334 (99.8) | 7692 (99.8) | 642 (99.8) | |
| Patient Status at Censoring, n (%) | ||||
| Alive (in site) | 5765 (69.0) | 5320 (69.0) | 445 (69.2) | .29 |
| LTFU | 1533 (18.4) | 1425 (18.4) | 108 (16.8) | |
| Transferred | 953 (11.4) | 873 (11.4) | 80 (12.4) | .31 |
| Died | 83 (1.0) | 73 (1.0) | 10 (1.6) | |
| Withdrew | 18 (0.2) | 18 (0.2) | 0 (0) | .14 |
Abbreviations: cART, combination antiretroviral therapy; HIV, human immunodeficiency virus; IQR, interquartile range; LTFU, loss to follow up.