Table 2.
Rule | Prediction | Reference |
---|---|---|
IRF > =1 | GM12878 (lymphoblastoid cells) | [46, 47] |
JDP2 > =1 | HeLa-S3 (cervical carcinoma cells) | [54] |
AP1 > =9 & HESX1 > =2 & LMO2 > =2 | AP1 [48, 49] | |
EMX1 < =11 & ETS < =12 & HNF4 > =1 | HepG2 (liver cancer cells) | HNF4 [50], ETS [69] |
HNF4 > =1 & IRF4 < =4 & RUNX2 < =4 & TAL1 < =4 | HNF4 [50] | |
ALX3 < =26 & EVX1 > =6 & GATA > =2 & LMO2 > =2 | K562 (immortalised myelogenous leukaemia cells) | GATA [52, 53], LMO2 [51] |
GATA > = 4 & HNF4 = 0 & POU4F3 < =4 | GATA [52, 53] | |
No rule identified | A549 (adenocarcinomic alveolar basal epithelial cells) |
The numbers in the rules represent the motif frequency detected in the +/− 120 bp regions from the peak centre