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. 2017 Nov 14;15(1):1177–1183. doi: 10.3892/ol.2017.7401

Figure 5.

Figure 5.

P53, BAX and CASP3 are upregulated while BCL-2 is downregulated in the PDCD5 overexpressing A431 cells. (A) The transcript levels of P53, BAX, BCL-2 and CASP3 in the PDCD5 overexpressing A431 cells and its control cells were analyzed by real-time RT-PCR. (B) The expression levels of P53, BAX, BCL-2 and CASP3 in the PDCD5 overexpressing A431 cells and its control cells were examined by western blot. GAPDH was used as a loading control. (C) Quantification for western blot data in (B) from there independent experiments. *P<0.05, **P<0.01 and ***P<0.001. Control, empty vector-transfected A431 cells; PDCD5, PDCD5 overexpressing A431 cells.