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Stability and biological activity effects of emulsion components
| Component | Structural classes evaluated | Effect on emulsion stability | Effect on vaccine adjuvant activity |
|---|---|---|---|
| Oil | Triterpene | − | ++ |
| Triglyceride | |||
| Emulsifier | Polysorbate | ++ | − |
| Poloxamer | |||
| Phospholipid | |||
| Excipients | Buffer | + | − |
| Isotonic agent | |||
| Antioxidant |
Qualitative rating of the component effects on stability or biological activity: large effect (++), some effect (+), little or no effect (−).
