Table 1.
Characteristics of cases and controls in association analysis
| Clinical data | Control (n = 270) | Casea (n = 265) | P |
|---|---|---|---|
| Age (years) | 57.72 ± 10 | 58.03 ± 9.5 | 0.716b |
| Male gender | 150 (56%) | 154 (58%) | 0.601c |
| Hypertension | 93 (34%) | 169 (64%) | < 0.001 c |
| Hyperlipidemia | 63 (23%) | 100 (38%) | < 0.001 c |
| Diabetes | 66 (24%) | 106 (40%) | < 0.001 c |
| TC (mmol/L) | 4.36 ± 0.55 | 4.37 ± 1.07 | 0.832b,d |
| TG (mmol/L) | 1.01 (0.77~1.28) | 1.35 (1.00~1.92) | < 0.001 d,e |
| HDL-C (mmol/L) | 1.26 (1.13~1.42) | 1.10 (0.94~1.34) | < 0.001 d,e |
| LDL-C (mmol/L) | 2.57 ± 0.36 | 2.43 ± 0.88 | 0.017 b,d |
| FBG (mmol/L) | 4.71 (4.35~5.15) | 5.84 (5.31~6.87) | < 0.001 e |
| PBLs counts (10 9 /L) | 5.30 (4.60~6.29) | 6.58 (5.33~7.92) | < 0.001 e |
| PBLs classifications (PBMCs %) | 40.31 ± 8.11 | 34.48 ± 10.16 | < 0.001 b |
| 5-mC contents (5-mC/C %) | 4.42 ± 0.87 | 3.90 ± 0.63 | < 0.001 b,f |
Data are presented as mean ± SD or as median (inter-quartile range). Italic letters show the significant associations and their P values. PBL classifications were calculated by percentages of PBMCs in PBLs
aThe CAD patients are consists of 71 (27%) myocardial infarction and 194 (73%) angina pectoris, respectively
bStudent’s t test
cχ2 test
dMost of the CAD patients with hyperlipidemia were under anti-hyperlipidemia therapy in the case group
eMann-Whitney U test
fP = 1.10 × 10− 14