Table 3.

Associations between global 5-mC contents and CAD

	Odds ratio (95% CI)	P value
Not adjusted	0.397 (0.308, 0.512)	1.15 × 10−12
Adjusted for age and sex	0.393 (0.304, 0.507)	8.40 × 10−13
Plus histories of HT, HL, and DM	0.388 (0.295, 0.511)	1.66 × 10−11
Plus PBL counts	0.355 (0.262, 0.481)	2.54 × 10− 11
Plus PBL classifications	0.325 (0.237, 0.445)	2.62 × 10−12

The OR value represents altered risk of CAD odds per unit change in global 5-mC contents. Odds ratio less than 1 indicates that the independent factor (i.e., global 5-mC contents) is a protective factor