Table 4.
Associations of global 5-mC contents with CAD prevalence
| Bottom tertilea | Middle tertile | Per SD decrease | |
|---|---|---|---|
| Not adjusted | 3.974 (2.552, 6.189) | 3.393 (2.183, 5.237) | 2.517 (1.951, 3.245) |
| Adjusted for age and sex | 4.044 (2.589, 6.316) | 3.433 (2.203, 5.349) | 2.546 (1.971, 3.289) |
| Plus histories of HT, HL, and DM | 4.048 (2.509, 6.532) | 3.446 (2.153, 5.516) | 2.577 (1.956, 3.395) |
| Plus PBL counts | 5.165 (3.049, 8.750) | 4.012 (2.391, 6.731) | 2.816 (2.077, 3.816) |
| Plus PBL classifications | 5.667 (3.312, 9.699) | 4.195 (2.482, 7.093) | 3.076 (2.245, 4.213) |
Data are odds ratio (95% CI). Odds ratio more than 1 indicates that the independent factor (i.e., global 5-mC contents divided in each group) is a risk factor. The top tertile was used as the reference group. Tertile cut-points were 3.77 and 4.43%, respectively, based on global 5-mC distributions among the whole samples (i.e., 535 participants)
aFor trend, P < 0.001