Table 5.
Characteristics of case and control subgroups in PBL subtype analysis
| Clinical data | Control (n = 50) | Casea (n = 50) | P |
|---|---|---|---|
| Age (years) | 64 ± 9.5 | 62 ± 9.9 | 0.248b |
| Male gender | 26 (52%) | 27 (54%) | 0.84c |
| Hypertension | 16 (32%) | 31 (62%) | 0.003 c |
| Hyperlipidemia | 9 (18%) | 19 (38%) | 0.026 c,d |
| Diabetes | 10 (20%) | 21 (42%) | 0.017 c |
| PBLs counts (10 9 /L) | 5.48 (4.56~6.65) | 6.63 (5.63~9.28) | 0.001 e |
| Neutrophil (%) | 59.22 ± 10.55 | 66.01 ± 11.45 | 0.003 b |
| Lymphocyte (%) | 30.28 ± 8.46 | 24.08 ± 9.72 | 0.001 b |
| Monocyte (%) | 7.72 ± 2.78 | 7.47 ± 2.47 | 0.625b |
| 5-mC contents (5-mC/C %) | 4.11 ± 0.73 | 3.75 ± 0.76 | 0.017 b |
| 5-hmC contents (5-hmC/C %) | 0.0163 ± 0.0052 | 0.0191 ± 0.0048 | 0.005 b |
| DNMT1 expressions | 0.0084 ± 0.0058 | 0.0064 ± 0.0029 | 0.006 b |
Data are presented as mean ± SD or as median (inter-quartile range). Italic letters show the significant associations and their P values
aThe CAD patients are consists of 14 (28%) myocardial infarction and 36 (72%) angina pectoris, respectively
bStudent’s t test
cχ2 test
dMost of the CAD patients with hyperlipidemia were under anti-hyperlipidemia therapy in the case group
eMann-Whitney U test