Figure 6.

Action potentials recorded simultaneously after adding simulated I_K1. (A) Action potentials from 3 cells recorded in parallel on a Patchliner Quattro. (B) Simulated I_K1 was recorded for each of the 3 cells and is shown. Note the brief increase in I_K1 during the upstroke of the action potential, where I_K1 channels respond with increased current to the depolarization induced by the pacing stimulus, which is in line with the slight decrease observed in upstroke velocity with increasing I_K1 conductance.